NaNotics to work with Mayo on nanomedicine cancer therapy

NaNotics LLC (Mill Valley, California) has announced that it will work with the Mayo Clinic to develop a cancer treatment known as NaNots that works by depleting targeted pathogenic molecules from the blood. The NaNot would target a soluble form of programmed death-ligand 1 (PD-L1), a tumor-generated immune inhibitor, while ignoring membrane forms of PD-L1.

“Our team has been studying sPD-L1 for several years,” said Dr. Sean Park, an oncologist at Mayo Clinic, in a statement. “We believe it’s a key driver of immune evasion for many tumor types.”

Park said the ability to home in on soluble PD-L1 is “potentially significant.”

“We’re excited to collaborate with NaNotics and test NaNots against sPD-L1 in humans for the first time,” he added.

NaNot image courtesy of NaNotics

NaNotics hopes to file an investigational new drug (IND) application with the FDA to begin human clinical trials within…

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Mayo Clinic expands plans for new research lab in Minnesota

A rendering of the Anna-Maria and Stephen Kellen Building. [Image courtesy of Mayo Clinic]

The Mayo Clinic is roughly tripling the size of the new research lab it plans to build in its home city of Rochester, Minn.

Before the COVID-19 hit, plans called for a four-story building. But officials at the top-tier health provider say the pandemic taught them that scientific advancements need to accelerate in healthcare. The Anna-Maria and Stephen Kellen Building will now be 11 stories and 176,000  ft2 upon its completion, scheduled for the fourth quarter of 2023.

Get the full story on our sister site Medical Design & Outsourcing. 

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Mayo Clinic expands plans for new research lab in Minnesota

A rendering of the Anna-Maria and Stephen Kellen Building. [Image courtesy of Mayo Clinic]

The Mayo Clinic is roughly tripling the size of the new research lab it plans to build in its home city of Rochester, Minn.

Before the COVID-19 hit, plans called for a four-story building. But officials at the top-tier health provider say the pandemic taught them that scientific advancements need to accelerate in healthcare. The Anna-Maria and Stephen Kellen Building will now be 11 stories and 176,000  ft2 upon its completion, scheduled for the fourth quarter of 2023.

“Research is a key pillar of our 2030 strategy,” Mayo Clinic CEO Dr. Gianrico Farrugia said in a late April news release. “We’re committed to advancing more cures, connecting more patients to our expanded expertise, and transforming health care for people everywhere. And that transformation starts with research.”

The new…

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NXgenPort, Mayo Clinic ink license agreement over chemo-port catheter for home monitoring

NXgenPort today announced that it has entered into a license agreement with Mayo Clinic to develop and test an implantable chemo-port catheter.

NXgenPort’s technology has chemo-port efficacy with sensor technology to measure and remotely monitor the early onset of complications by reporting and tracking patient response during treatment.

Get the full story on our sister site, Medical Tubing + Extrusion.

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Mayo Clinic helps launch two new companies for improved diagnostics

Mayo Clinic announced that it is introducing a new technology platform to support two new companies it has launched.

Rochester, Minn.–based Mayo Clinic’s Remote Diagnostics & Management Platform (RDMP) is designed to connect data with new AI algorithms and augment human decision-making within existing clinical workflows, according to a news release.

Get the full story at our sister site, MassDevice.

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BioSig, Mayo Clinic announce AI development partnership

The Pure EP system [Image courtesy of BioSig Technologies]

BioSig Technologies (NSDQ:BSGM) will work with the Mayo Foundation for Medical Education and Research to develop next-gen, AI-powered software for its  Pure EP system, which is meant to take electrophysiology to the next level.

The Mayo Clinic has already been an important investor and development partner for the Westport, Conn.–based company. BioSig signed a 10-year collaboration agreement with Mayo Clinic in March 2017, signing three new patent and know-how license agreements with the Mayo foundation in November 2019.

The new R&D collaboration, announced yesterday, will find ways to use artificial intelligence and machine learning to boost the clinical value of Pure EP and its proprietary hardware and software with advanced signal processing capabilities. Dr. Samuel J. Asirvatham, Mayo Clinic’s vice chair of innovation and Electrophysiology…

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Mayo Clinic needed to engineer its way through COVID-19: Here’s what they did.

The health system’s medical and engineering staffs had to devise their own solutions for lab gear, PPE and operating room air decontamination.

[Image courtesy of Mayo Clinic]

As COVID-19 settles into several regions of the U.S., healthcare systems that once sat on the sidelines likely will find themselves in the same situation as their counterparts in the Northeast did earlier this year.

While this may serve as little comfort, hospitals in regions getting hit by the new wave of the deadly virus do have the benefit of seeing how hospitals in the Upper Midwest and the Northeast managed the pandemic.

One of the easiest — or at least most evident — lessons available is the use of additive manufacturing or 3D printing. Mayo Clinic and other hospital systems, including Beth Israel Lahey in Boston, used their 3D printers to produce critical personal protective equipment (PPE) such as masks and face shiel…

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Mayo Clinic needed to engineer its way through COVID-19: Here’s what they did.

The health system’s medical and engineering staffs had to devise their own solutions for lab gear, PPE and operating room air decontamination.

[Image courtesy of Mayo Clinic]

As COVID-19 settles into several regions of the U.S., healthcare systems that once sat on the sidelines likely will find themselves in the same situation as their counterparts in the Northeast did earlier this year.

While this may serve as little comfort, hospitals in regions getting hit by the new wave of the deadly virus do have the benefit of seeing how hospitals in the Upper Midwest and the Northeast managed the pandemic.

One of the easiest — or at least most evident — lessons available is the use of additive manufacturing or 3D printing. Mayo Clinic and other hospital systems, including Beth Israel Lahey in Boston, used their 3D printers to produce critical personal protective equipment (PPE) such as masks and face shiel…

Read more
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