One of the first focuses of organ-chip specialist Emulate (Boston) was to reduce the need for animal testing over time. Its technology can simulate tissue-tissue interfaces within organs using human cells.
But the potential of the organ chips to yield mechanistic insights for drug discovery and understanding toxicities has become more evident over time.
The pandemic has underscored that promise, highlighting the potential of Emulate’s technology for drug discovery and vaccine testing.
A spinout of the Wyss Institute for Biologically Inspired Engineering at Harvard University, Emulate’s human airway chip culture was highlighted earlier this year in Nature Biomedical Engineering.
Created with microchip manufacturing techniques and microfluidic culture technology, Emulate’s organ chips contain living human cells that simulate organ-level functions. The organ chips can “recreate tissue-tissue interfaces, which is what defines an organ,” said Dr. D…