Multiple COVID-19 vaccine doses associated with lower symptom burden

Doses of the COVID-19 vaccine at Walter Reed National Military Medical Center, Bethesda, Md. [DoD photo by Lisa Ferdinando.]

A study of essential and frontline workers infected with COVID-19 found that recent vaccination was associated with a variety of benefits. In particular, the workers who had received two or three mRNA COVID-19 vaccine doses had lower viral loads than the unvaccinated. They also had fewer fever and chill symptoms and were less likely to require medical care.

Published in JAMA, the study involved 1,199 participants from Arizona, Florida, Minnesota, Oregon, Texas and Utah. Volunteers were subjected to weekly nasal swabs regardless of symptoms from December 14, 2020, to April 19, 2022. The median age of participants was 41.

The study period encompassed both the delta and omicron waves in the U.S.

The delta variant was more likely to be symptomatic. Only 3.9% of those infected wit…

Read more
  • 0