Urovant’s Gemtesa (vibegron) was the subject of two presentations at the Annual Meeting of the American Urological Association (AUA2021).
The first explained that vibegron is effective in patients with ‘dry’ overactive bladder (OAB) based on a post-hoc analysis of the pivotal EMPOWUR trial. The second presentation explained that vibegron had a negligible impact on ambulatory blood pressure in a randomized, double-blind, placebo-controlled study.
Vibegron, a beta-3 agonist, stands out in a market of overactive bladder drugs that are primarily antimuscarinics. “There’s only one other beta-3 agonist on the market,” said Dr. David Staskin, who was the international lead investigator in the EMPOWUR trial.
The drug is also unique in that its label includes data on urgency associated with OAB. “It’s the first time [urgency] has ever been in a package insert for any overactive bladder drug,” said Staskin, who is also an associate professor of urology at Tuft…