10 promising oncology drug candidates

[3-D model of adagrasib molecule from PubChem]

The risk of cancer deaths has fallen steadily in recent years. Before the pandemic, the risk of death from cancer fell roughly 2% annually from 2015 to 2019. In the 1990s, the risk of cancer death fell approximately 1% each year, according to the American Cancer Society. In addition to improved screening and diagnosis, cancer survival rates have fallen as a result of therapeutic breakthroughs.

In this feature, we round up a variety of oncology drug candidates that may prove to be promising cancer therapeutics in the coming years.

1. Adagrasib

Adagrasib from Mirati Therapeutics is a KRASG12C inhibitor. In 2021, the drug candidate won Breakthrough Therapy Designation for patients with advanced non-small cell lung cancer (NSCLC) with the KRASG12C mutation. The KRAS protein inhibitor has been the subject of 14 trials to date, including a Phase 3 study focused on …

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