single-use technologies Archives - Medical Design Sourcing

The G3 Electronic Fieldbus Platform complements Emerson’s AVENTICSSeries 501 Pneumatic Valve Manifold. The graphic display for configuration and diagnostics is compatible with various communication protocols, such as Ethernet IP, ProfiNet and DeviceNet. Photo courtesy of Emerson.

With the rise of biologics and personalized medicine, the biopharmaceutical industry is adding single-use technologies (SUTs) to their manufacturing options. Manufacturers are realizing the benefits of being agile, and many are adopting SUTs to turn over smaller batches of new products quickly and efficiently. Single-use technologies use disposable bioprocessing equipment, such as bags and flexible tubing, instead of conventional, permanent stainless steel systems. By eliminating the time-consuming clean-in-place (CIP) and steam-in-place (SIP) processes between batches, SUTs speed up the changeover time and greatly reduce the costs of ener…

To fast-track the time to market and gain a competitive edge, pharmaceutical development companies are increasingly implementing single-use technologies (SUT). Single-use technologies are built using an array of components, including sampling bottles, filters, Luer locks, seals and dispensing tips. The technology can be as simple as a single assembly. Or it can be an entire system made up of multiple complex assemblies used across the entire manufacturing process, including formulation, upstream/downstream processing and final product filling.

SUT offers many benefits compared to traditional stainless-steel systems, such as eliminating clean-in-place or steam-in-place (CIP/SIP) requirements, faster changeovers between batches resulting in reduced production time, more flexible infrastructure, and a decreased risk of cross-contamination.

Although standard, off-the-shelf SUT assemblies are currently available, most narrowly focus on upstream processes that use ki…

single-use technologies

Single-use technologies gain wide adoption in biomanufacturing

Outsourcing single-use technologies to accelerate speed to market