2024 forecast: Navigating new frontiers in pharma with AI, synthetic data, and strategic partnerships

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In late 2022, we published a series of predictions, which, among other things, projected that 2023 would be a “massive showcase” for machine learning (ML) in drug discovery and development. And in many ways, 2023 was a pivotal year for AI in pharma. This evolution in AI and ML applications in pharma built upon the groundwork laid in 2022, a year in which the pharma sector embraced digital components, dynamic clinical trial designs, and advanced data science initiatives related to radiomics. Now, the ongoing focus on ML for processing large volumes of molecular, biochemical, and genomic data continues to lay the groundwork for innovation in 2024.

The predictions for 2024 further emphasize the importance of data, in both structured and unstructured formats, while also touching on a range of other themes related to everything from pharma partnerships with virtual care providers to the challenges and s…

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Anticipating IND submission: Ensuring your drug is ready for preclinical toxicology studies 

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Drug development is often a vast and intricate journey. Each phase signifies an advancement in the process, always with an eye toward patient safety and efficacy. But before any therapeutic finds itself on the bedside tables of hopeful patients, it faces a formidable challenge: preclinical toxicology testing. As the gateway to clinical trials, this early testing is more than just a safety assessment. A robust examination establishes a drug’s potential efficacy, possible adverse reactions, and activity within the human body.

Preclinical toxicology is when a drug’s strengths and vulnerabilities are laid bare for all to see. Imagine the invaluable insights drawn from organ-specific tests that reveal hidden adverse reactions or genotoxicity evaluations that shine a light on the risks of cellular mutations.

Such revelations can influence everything from dosing decisi…

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