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Can the U.S. unify around psychedelics for mental health?

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The U.S. has perhaps never been more divided than it is today. Americans are divided over politics and myriad social issues, COVID-19, climate change, immigration and seemingly everything else.

Not surprisingly, opinions also diverge on whether psychedelic drugs have therapeutic potential. Earlier this year, a survey from The Harris Poll found that 65% of Americans with anxiety, depression or PTSD believe that drugs such as the classic psychedelic psilocybin and the empathogen methylenedioxymethamphetamine (MDMA) should be available for therapeutic use. The compounds remain Schedule I drugs but could find FDA approval in the coming years.

Mental health professionals have tended to view psychedelics skeptically after they were illegal in the 1970s. A 2018 survey in The Journal of Nervous and Mental Disease found that psychiatrists tended to view psychedelics as “potent…

How psychedelics could address unmet need in mental health

[Image courtesy of Pixabay]

Interest in the therapeutic potential of psychedelics is booming, given their therapeutic potential for treating depression and other conditions. It is telling that psychedelics were among the hottest topics at the World Economic Forum (WEF) meeting this year in Davos, Switzerland, prompting mockery from late-night comics.

Although the field remains embryonic, part of the reason for the recent interest in psychedelics is their potential to address difficult-to-treat mental health conditions. For example, research such as the U.S. government-backed Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study “showed us that our available medications are not as effective as we’d hoped they would be,” said Dr. John Krystal, chair of the department of psychiatry at Yale University, in a recent webinar from Cybin (Toronto, Canada). For depressed who respond to s…

PurMinds believes psychedelics hold promise for neurological conditions

Interest in psychedelics has ratched up in recent years and a growing number of drug companies are beginning to explore their potential to treat everything from depression to neurodegeneration.

“It is a really really exciting time,” said Aron Buchman, chief strategy officer, PurMinds BioPharma, which is exploring psychedelics’ potential to treat neurological diseases.

American author Michael Pollan recently surmised in an interview with Independent that the psychedelics industry was in a “gold rush” phase. “Whether it’s going to work is another question. I think it’s going to be very challenging to fit into the system,” Pollan added.

Headquartered in North York, Ontario, PurMinds is based in a country that is warming up to the therapeutic potential of psychedelics. The Canadian government has granted a number of patients a federal dispensation covering the therapeutic use of p…