NVIDIA and AWS collaborate to bring BioNeMo AI platform to the cloud

3D protein structure prediction with AlphaFold2, OpenFold, and ESMFold in NVIDIA’s BioNeMo. [NVIDIA]

Chipmaker NVIDIA and cloud behemoth AWS have been partnering for years, and now the two companies are announcing that NVIDIA’s drug discovery generative AI platform, BioNeMo, is now available on AWS. Additionally, plans are underway for BioNeMo to be offered on AWS on NVIDIA DGX Cloud.

The alliance was announced at the AWS re:Invent event. Startups including Evozyne, Etcembly and Alchemab are early AWS users using BioNeMo for generative AI-accelerated drug discovery and development.

Evozyne focuses on creating novel proteins for therapeutic development, Etcembly is building a large machine learning database for immunology and TCR immunotherapies, and Alchemab specializes in identifying protective antibodies for hard-to-treat diseases.

Last week, NVIDIA announced a collaboration with Genentech with BioNeMo also playing a ke…

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Decoding the enigma of the commander complex: Employing AlphaFold2 to illuminate biological structures

The commander complex. [New image from Institute for Molecular Bioscience The University of Queensland]

Machine learning algorithms, such as Alphabet’s neural network-based model AlphaFold2, are steadily transforming medical research, shedding light on complex biological structures. A recent case in point involves research using the technology to explore the Commander complex, a 16-protein complex crucial for cellular protein transport processes. This complex is not only vital for normal cellular function, but it’s also associated with several diseases, making it a potential target for novel therapies. Scientists at the Universities of Bristol and Queensland (Australia) and the Medical Research Council Laboratory of Molecular Biology in Cambridge, collaborated on the research.

The renowned journal Cell published the study, titled “Structure of the endosomal Commander complex linked to Ritscher-Schinzel syn…

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