peanut allergy

Intrommune extends scope of Phase 1 trial for peanut-allergy-treating toothpaste

The food-allergy-focused biotech Intrommune Therapeutics is announcing that it is extending the duration of the ongoing Phase 1 OMEGA clinical trial of INT301 in adults with peanut allergy.

The alteration will lengthen the study duration to 48 weeks to include a maintenance period.

The study duration was previously 26 weeks.

The New York City–based company is also amending the study to include a double-blind placebo-controlled oral food challenge (DBPCOFC) at the end of the therapy period.

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Intrommune extends scope of Phase 1 peanut allergy trial

The food-allergy-focused biotech Intrommune Therapeutics is announcing that it is extending the duration of the ongoing Phase 1 OMEGA clinical trial of INT301 in adults with peanut allergy.

The alteration will lengthen the study duration to 48 weeks to include a maintenance period.

The study duration was previously 26 weeks.

The New York City–based company is also amending the study to include a double-blind placebo-controlled oral food challenge (DBPCOFC) at the end of the therapy period.

The OMEGA clinical trial design is double-blinded and placebo-controlled. The study enrolls adults with peanut allergy in a three-to-one ratio to receive escalating doses of INT301 or placebo.

INT 301 is a mucosal peanut-desensitization immunotherapy. The product is formulated as a toothpaste to be incorporated into patients’ daily oral hygiene routine.

“We continue to make steady progress in the clinical development of INT301 for peanut allergy. W…