Indication: Difficult-to-treat hypertension Estimated peak sales: $2.5 billion The investigational hypertension drug aprocitentan from Idorsia Pharmaceuticals (SWX:IDIA) is a dual endothelin receptor antagonist. By blocking the peptide endothelin, the drug can block the constriction of blood vessels, thereby lowering blood pressure.
In late January, Idorsia submitted for European authorization to market aprocitentan for treatment-resistant hypertension. The compan…