Kyverna Therapeutics wins $85 million in Series B financing

The cell therapy company Kyverna Therapeutics (Emeryville, California) has closed an oversubscribed $85 million Series B funding round led by Northpond Ventures.

The company plans to use the funding to launch a Phase 2 trial for its lead asset, KYV-101, in the first half of 2022.

KYV-101 is an autologous anti-CD19 chimeric antigen receptor T-cell (CAR T) construct with potential applications in B cell-driven autoimmune diseases, including lupus nephritis, systemic sclerosis and inflammatory myopathies.

Kyverna secured rights to KYV-101 from the National Institutes of Health (NIH) for autologous and allogeneic CAR T-cell therapies.

Kyverna will also use the most recent funding to further the development of KYV-201, an investigational candidate that integrates its CD19 CAR T construct with Intellia’s (NSDQ:NTLA) ex vivoCRISPR/Cas9-based allogeneic platform.

The company also intends to use its recent funding to bolster its development activiti…

Read more
  • 0

SimBioSys secures $15 million in Series A funding for computational oncology software

The developer of a cloud-based application for oncology care and research, SimBioSys, has raised $15 million in Series A funding. Genoa Ventures and Northpond Ventures led the funding round, which also involved AV8 Ventures, Heritage Medical Group, and Mayo Clinic.

SimBioSys also announced that existing investors and its founders participated in the financing, raising a total of $21 million.

The company plans on using the funds for the development and commercialization of its TumorScope software platform. In particular, the company plans on using the funding to digitize and model treatment options for a number of solid tumors, including in breast cancer.

TumorScope is a cloud-based application that virtualizes cancer in three dimensions. The company reports that it can accurately simulate how a patient’s tumor will respond to a variety of therapies following diagnosis. “Simulating a response before prescribing treatment is a significant stride in p…

Read more
  • 0