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Ovid Therapeutics taps Robert Langer to lead scientific advisory board

Biopharma Ovid Therapeutics (NSDQ:OVID) has named MIT professor Robert Langer as the chair of its scientific advisory board.

The company focuses on rare neurological diseases.

“The neurosciences are on the cusp of a scientific and, hopefully, therapeutic revolution,” said Langer in a statement. “Ovid has an exciting approach to tackling the key questions that drive scientific research and new medicines in the central nervous system.”

Get the full story from our sister site, Drug Discovery & Development.

MIT, Indian researchers grow tiny brains in 3D-printed bioreactor

Scientists in Cambridge, Mass. and Chennai, India, are touting self-organizing brain tissue growth in a 3D-printed system.

Published results in Biomicrofluidics highlight the work of the Massachusetts Institute of Technology (MIT) and Indian Institute of Technology Madras scientists, who have grown small amounts of the self-organizing brain tissue, known as organoids, in a tiny 3D-printed system that allows for observation while they grow and develop, according to a news release.

Get the full story at our sister site, Medical Design & Outsourcing.

MIT, Indian researchers grow tiny brains in 3D-printed bioreactor

Scientists in Cambridge, Mass. and Chennai, India, are touting the growth of self-organizing brain tissue in a 3D-printed system.

Published results in Biomicrofluidics highlight the work of the Massachusetts Institute of Technology (MIT) and Indian Institute of Technology Madras scientists, who have grown small amounts of the self-organizing brain tissue, known as organoids, in a tiny 3D-printed system that allows for observation while they grow and develop, according to a news release.

Get the full story at our sister site, Medical Design & Outsourcing.

MIT, Indian researchers grow tiny brains in 3D-printed bioreactor

Scientists in Cambridge, Mass. and Chennai, India, are touting the growth of self-organizing brain tissue in a 3D-printed system.

Published results in Biomicrofluidics highlight the work of the Massachusetts Institute of Technology (MIT) and Indian Institute of Technology Madras scientists, who have grown small amounts of the self-organizing brain tissue, known as organoids, in a tiny 3D-printed system that allows for observation while they grow and develop, according to a news release.

Technology for real-time observation of growing organoids currently involves commercial culture dishes with many wells in a glass-bottomed plate placed under a microscope. The plates are costly and only compatible with specific microscopes while they don’t allow for the flow or replenishment of a nutrient medium to the growing tissue, the researchers say.

Advances have led to microfluidics, which delivers a nutrient medium through small tubes connected to a tiny pla…

MIT researchers tout new machine learning technique for assessing drug molecules

MIT researchers have developed a machine learning-based technique to more quickly calculate the binding affinity of a drug molecule (represented in pink) with a target protein (the circular structure). [Image courtesy of MIT News]

MIT researchers are touting a new machine-learning technique called DeepBAR that can quickly calculate the binding affinities between drug candidates and their targets.

DeepBAR produces precise calculations in a fraction of the time compared to previous, according to the researchers. They think the software could potentially accelerate drug discovery and protein engineering.

“Our method is orders of magnitude faster than before, meaning we can have drug discovery that is both efficient and reliable,” Bin Zhang, an MIT chemistry professor and a co-author of a new paper describing the technique, said in an MIT news release.

The research, which NIH partially funded, appea…

3M, MIT working on paper-based, rapid COVID-19 test

The 3M COVID-19 test team works at at the pilot lab facility at 3M’s Minnesota headquarters. (Image courtesy of 3M)

3M (NYSE:MMM) announced today that it is working with Massachusetts Institute of Technology (MIT) researchers to develop a paper-based, rapid test to detect the virus that causes COVID-19, with the potential to manufacture millions of tests per day.

The test would detect viral antigens and deliver “highly accurate results within minutes” via a paper-based device, according to the Maplewood, Minn.-based company. It could be administered at the point-of-care and would not need to be sent to labs for testing.

The National Institutes of Health (NIH) selected the rapid COVID-19 test for accelerated development and commercialization support, after review by an expert panel, 3M added. Researchers received $500,000 in validation funding from the Rapid Acceleration of Diagnostic…

MIT researchers may have invented a safer way of splitting ventilators

[Image courtesy of MIT]MIT and Brigham and Women’s Hospital researchers say they have a way of splitting ventilators which could address many of the safety concerns — potentially boosting the supply of ventilators amid the COVID-19 pandemic.

They have demonstrated their concept’s effectiveness in the lab — but they still caution it should be used only as a last resort during an emergency when a patient’s life is at stake.

Ventilators should only be shared as a last resort. One problem: Patients sharing the ventilator must all have the same lung capacity. If one patient’s lung function improves or another’s deteriorates, one patient may receive the right amount of air but other may be out of luck.

Basically the MIT team incorporated flow valves, one for each patient’s branch, that allow them to control the amount of air that each receives. “These flow valves allow you to personalize the flow to each patient based on their needs. They also ensure that if o…

MIT researchers may have invented a safer way of splitting ventilators

[Image courtesy of MIT]

MIT and Brigham and Women’s Hospital researchers say they have a way of splitting ventilators which could address many of the safety concerns — potentially boosting the supply of ventilators amid the COVID-19 pandemic.

They have demonstrated their concept’s effectiveness in the lab — but they still caution it should be used only as a last resort during an emergency when a patient’s life is at stake.

Ventilators should only be shared as a last resort. One problem: Patients sharing the ventilator must all have the same lung capacity. If one patient’s lung function improves or another’s deteriorates, one patient may receive the right amount of air but other may be out of luck.

Basically the MIT team incorporated flow valves, one for each patient’s branch, that allow them to control the amount of air that each receives. “These flow valves allow you to personalize the flow to eac…

MIT researchers may have invented a safer way of splitting ventilators

[Image courtesy of MIT]

MIT and Brigham and Women’s Hospital researchers say they have a way of splitting ventilators which could address many of the safety concerns — potentially boosting the supply of ventilators amid the COVID-19 pandemic.

They have demonstrated their concept’s effectiveness in the lab — but they still caution it should be used only as a last resort during an emergency when a patient’s life is at stake.

Ventilators should only be shared as a last resort. One problem: Patients sharing the ventilator must all have the same lung capacity. If one patient’s lung function improves or another’s deteriorates, one patient may receive the right amount of air but other may be out of luck.

Basically the MIT team incorporated flow valves, one for each patient’s branch, that allow them to control the amount of air that each receives. “These flow valves allow you to personalize the flow…