Researchers at MIT and Beth Israel Deaconess Medical Center are exploring a yeast-based alternative to RNA vaccines.
A new paper highlights a vaccine, which comprises fragments of the SARS-CoV-2 spike protein arrayed on a virus-like particle, that reportedly elicited a strong immune response and protected animals against viral challenge, according to a post on MIT’s website.
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A new protein subunit vaccine developed at MIT and Beth Israel Deaconess Medical Center may offer an inexpensive, easy-to-store, and effective alternative to RNA vaccines for Covid-19. Pictured is a schematic of the vaccine.[Image from Jose-Luis Olivares, MIT, and figures courtesy of the researchers]
Researchers at MIT and Beth Israel Deaconess Medical Center are exploring a yeast-based alternative to RNA vaccines.A new paper highlights a vaccine, which comprises fragments of the SARS-CoV-2 spike protein arrayed on a virus-like particle, that reportedly elicited a strong immune response and protected animals against viral challenge, according to a post on MIT’s website.
The researchers designed the vaccine to be produced by yeast, using fermentation facilities that already exist around the world. MIT said the Serum Institute of India — the world’s largest vaccine manufacturer — is now prod…
[Image courtesy of the researchers]
Researchers at MIT are touting a novel method to synthesize a natural compound that has shown potential as an antibiotic.The chemists produced himastatin using the synthesis method and also managed to generate variants of the molecule, some of which showed antimicrobial activity, according to a news story from the university’s website. The compound appears to kill bacteria by disrupting cell membranes and it gives the researchers hope that they may design other molecules with even stronger antibiotic activity.
In 2016, details were released from the 2014 Review on Antimicrobial Resistance (AMR), commissioned by the UK government to address the concern that superbugs, resistant to current antibiotics, could eventually evolve to the point that the drugs are no longer effective. New Atlas reported at the time that, if such issues aren’t addressed, the AMR foun…
Researchers are developing injectable nanoparticles that can attract cells to help stop the bleeding at the site of an internal injury until a patient can reach a hospital for further treatment. In an effort to highlight the mechanism of action and safety of the particles, chemical engineers at MIT have studied how they circulate in the body and interact with the platelets that promote blood clotting.
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[Image courtesy of the MIT researchers]
MIT researchers are touting a machine learning model that can predict the complex that will form when proteins bind together.The technique represents an improvement on speed by somewhere between 80 and 500 times faster than state-of-the-art software methods and often predicts protein structures that are closer to actual structures that have been observed experimentally when two proteins bind together.
MIT researchers say their method could help scientists gain an understanding into biological processes that involve protein interactions, such as DNA replication and repair, according to the university’s website. It could also potentially increase the pace of new medicine development.
Octavian-Eugen Ganea and Xinyuan Huang are co-lead authors of the paper. MIT co-authors include Regina Barzilay and Tommi Jaakkola.
“Deep learning is very good at cap…
MIT engineers are working on an app that that identifies and quantifies food content, which can aid in carbohydrate counting for people with diabetes. [Image from MIT News]
MIT researchers are touting a platform aimed at helping patients maintain healthy glucose levels by streamlining the diabetes management process.The researchers say the steps of estimating the carbohydrate content of a meal, drawing blood to measure blood glucose levels, then calculating the proper insulin dose before injecting the insulin — which typically must be repeated for every meal — make it difficult to maintain a treatment regimen. Those researchers say they’ve developed a new approach that makes the process easier and more efficient while helping diabetes patients maintain their healthy glucose levels.
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The researchers say the steps of estimating the carbohydrate content of a meal, drawing blood to measure blood glucose levels, then calculating the proper insulin dose before injecting the insulin — which typically must be repeated for every meal — make it difficult to maintain a treatment regimen. Those researchers say they’ve developed a new approach that makes the process easier and more efficient while helping diabetes patients maintain their healthy glucose levels.
Get the full story at our sister site, Drug Delivery Business News.
The researchers say the battery, developed in the form of an ultra-long fiber, could enable a variety of wearable electronic devices and may even be used to make 3D-printed batteries in a multitude of shapes, according to a news release.
According to the researchers, they see possibilities for self-powered communications, sensing and computational devices that could be worn like ordinary clothing. Additionally, the researchers see the possibility for use in devices whose batteries could also double as structural parts.
Get the full story at our sister site, Medical Design & Outsourcing.
This submarine drone is powered by a 20-meter-long fiber battery that is wrapped on its surface. [Courtesy of the researchers]
Researchers at MIT say they developed a rechargeable lithium-ion battery in the form of a fiber that could be woven into fabrics.The researchers say the battery, developed in the form of an ultra-long fiber, could enable a variety of wearable electronic devices and may even be used to make 3D-printed batteries in a multitude of shapes, according to a news release.
According to the researchers, they see possibilities for self-powered communications, sensing and computational devices that could be worn like ordinary clothing. Additionally, the researchers see the possibility for use in devices whose batteries could also double as structural parts.
Published in the journal Materials Today, results from a proof of concept showed that the world’s longest flexible fiber b…
The Novo Nordisk Foundation, the Broad Institute of MIT and Harvard have launched an initiative to gain insights into disease mechanisms.
In an effort to accelerate efforts to mine genetic data for insights into mechanisms, and eventually rationally designed treatments, the trio of entities launched the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease based at the Broad Institute in Cambridge, Massachusetts.
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The researchers developed a way to precisely measure and map subtleties of tactile dexterity through the glove. The inside of the glove is threaded with sensors that detect, measure and map small changes in pressure across the glove. The individual sensors are highly attuned and can pick up weak vibrations across the skin, like from a person’s pulse.
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An MIT team of engineers has designed a new touch-sensing glove that can “feel” pressure and other tactile stimuli. The glove’s inside lining is studded with small, kernel-sized electrodes that can sense and map subtle changes in pressure.[Image courtesy of the researchers]
Engineers at MIT are touting a new, touch-sensing glove that can “feel” pressure and other tactile stimuli.The researchers developed a way to precisely measure and map subtleties of tactile dexterity through the glove. The inside of the glove is threaded with sensors that detect, measure and map small changes in pressure across the glove. The individual sensors are highly attuned and can pick up weak vibrations across the skin, like from a person’s pulse.
According to a news story posted on MIT’s website, the researchers believe the tactile glove could help to retrain motor function and coordination in people …