Johns Hopkins Archives - Medical Design Sourcing

Surgical robots don’t improve knee surgery revision rates, study says

[Image from Pixabay]

Robotically assisted total knee arthroplasty has skyrocketed in popularity, but a new registry data analysis raises some questions about the benefits for knee surgery patients.

The analysis of American Joint Replacement Registry (AJRR) data, presented at AAOS 2024 in San Francisco, found that revision rates were similar in conventional and robotic-assisted cementless TKA at two years post-operatively. The study also found that the odds of revision due to infection or mechanical loosening were not significantly different between the two methods.

“A lot of single surgeon studies show there is improved precision with robotic-assisted TKA,” Dr. Lucas Nikkel, assistant professor of orthopedic surgery at Johns Hopkins Medicine, said in a news release about the study. “Some studies suggest there may be improved early recovery or less damage to soft tissue. One of the chall…

New brain imaging technique delivers superscans with less data

A new algorithm, called DeepSTI, achieves a highly detailed 3D-reconstruction that shows magnetic susceptibility of tissues in the human brain. [Image courtesy of Johns Hopkins]

Researchers at Johns Hopkins University developed a new algorithm that can scan the brain for precise brain tissue susceptibility information.

Magnetic resonance imaging (MRI) offers images of the body that allow doctors to diagnose injury or illness. MRI’s susceptibility tensor imaging (STI) technique measures the magnetic susceptibility of different brain tissues. This information can help to better understand, diagnose and monitor neurological diseases like multiple sclerosis (MS) and Alzheimer’s.

The team at Johns Hopkins have a new algorithm for this technique, called DeepSTI. It takes data from multiple individual scans and provides a “super-scan” with brain tissue susceptibility information. The met…

Radiated, ‘humanized’ mice offer insights into implant rejection

A look at human immune cells that help explain implant rejection. [Image courtesy of Johns Hopkins]

Researchers at Johns Hopkins say they discovered an advanced “humanized” mouse model that helps predict the immune system’s reaction to medical implants.

The team set out to evaluate why human bodies frequently reject implanted biomaterials, Few ways currently exist to predict this or to prevent it from happening, the researchers said.

Joshua Doloff led the team, which included biomedical engineering graduate students Victor Quiroz and Amanda Rakoski. The team published the results from the model in Science Advances.

“By directly studying how human immune cells interact with implants in a mouse, we can unlock a much deeper level of mechanistic understanding of implant rejection responses,” said Doloff. “It’s our hope long-term that this newly identified humanized mouse model varian…

8 drug delivery innovations you need to know

The drug delivery space has seen plenty of innovation over the years and there are no signs of that slowing down any time soon.

Improvements upon established technologies like insulin delivery devices and inhalers have been presented by some, while others have unlocked new ways of delivering drugs through a variety of means.

Among the best innovations in the space are some of the heavy-hitting companies, like Medtronic and Tandem Diabetes Care. Some up-and-comers are beginning to make waves, too, while research continues to uncover new ways to deliver therapeutics.

Here are eight types of drug delivery innovations you should know:

Next>>

8 drug delivery innovations you need to know

The drug delivery space has seen plenty of innovation over the years and there are no signs of that slowing down any time soon.

Improvements upon established technologies like insulin delivery devices and inhalers have been presented by some, while others have unlocked new ways of delivering drugs through a variety of means.

Among the best innovations in the space are some of the heavy-hitting companies, like Medtronic and Tandem Diabetes Care. Some up-and-comers are beginning to make waves, too, while research continues to uncover new ways to deliver therapeutics.

Here are eight types of drug delivery innovations you should know:

Next>>