Pump supports precise biopharmaceutical dispensing applications

Intellitech’s i-FILL Micro is designed for manufacturers needing to automate R&D, lab or production filling of small volumes of high-value product with high accuracy.

Intellitech (Poland, Ohio) has introduced an i-FILL Micro pump that provides repeatable dispensing of biologics measuring 100 mcl to 15 ml with single stroke capacity. In addition, the pump supports larger volumes with multiple strokes.

The pump provides repeatable liquid filling accuracy of +/–0.5% of the intended volume.

A diaphragm and piston pump hybrid, the i-FILL Micro Pump can pump dry and does not drip between dispensing batches. This design can thus avoid wasting expensive products that are potentially worth thousands of dollars per milliliter.

The self-priming pump does not compress tubing while dispensing and thus does not cause shearing.

When used with the company’s sterile, single-use liquid measuring and d…

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Outsourcing single-use technologies to accelerate speed to market 

To fast-track the time to market and gain a competitive edge, pharmaceutical development companies are increasingly implementing single-use technologies (SUT). Single-use technologies are built using an array of components, including sampling bottles, filters, Luer locks, seals and dispensing tips. The technology can be as simple as a single assembly. Or it can be an entire system made up of multiple complex assemblies used across the entire manufacturing process, including formulation, upstream/downstream processing and final product filling.

SUT offers many benefits compared to traditional stainless-steel systems, such as eliminating clean-in-place or steam-in-place (CIP/SIP) requirements, faster changeovers between batches resulting in reduced production time, more flexible infrastructure, and a decreased risk of cross-contamination.

Although standard, off-the-shelf SUT assemblies are currently available, most narrowly focus on upstream processes that use ki…

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