Emerson debuts software for CIP applications 

[Image courtesy of Emerson]

Emerson (NYSE:EMR) has launched its new Clean In Place (CIP) Utilities and Automated Reporting Analytics package on its PACEdge and Movicon platforms on an industrial edge control device.

The food and beverage, and pharmaceutical industries use the clean- and steam-in-place method to clean fittings, vessels, filters, pipes and other internal surfaces without disassembly.

According to the company, the software can help industrial companies digitally transform manual and semi-automated systems by reducing utility consumption and energy use while also generating automated reports to enhance operations. The software can also help optimize process manufacturing by benchmarking against known cycles. In addition, it can help process manufacturers forecast energy use as well as water and resource consumption.

The new software is also designed to provide actionable data and an…

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Emerson introduces new three-way miniature solenoid valve

The new ASCO Series 090 three-way miniature solenoid valve [Image courtesy of Emerson]

Emerson (NYSE:EMR) announced the expansion of its ASCO Series 090 line of miniature solenoid valves.

The product line includes a new three-way Series 090 valve configuration. The three-way configuration enables lighter, more space-efficient solutions for gas control in oxygen therapy, compression therapy and gas analyzer devices, St. Louis–based Emerson said in a news release posted yesterday.

Originally developed as a two-way valve for air and inert gases in portable medical devices, the Series 090 valve features a compact architecture, small (10.8 mm footprint and 50-million-cycle life.

Because the Series 090 valve’s new three-way configuration can perform the same mixing and diverting functions as a pair of two-way valves, it provides more design flexibility for high-precision gas delivery systems for o…

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Ultrasonically welded flow sensor critical to success of Hamilton Medical ventilator design

The body of the Hamilton Medical proximal flow sensor consists of two molded halves composed of medical-grade plastic. [Photo courtesy of Hamilton Medical] The disposable sensor monitors ventilation of critically ill patients with high precision.

Didier Perret, Emerson

Hamilton Medical (Bonaduz, Switzerland) produces intelligent ventilation solutions for intensive-care units and critical-care transports. To meet the exploding demand for ventilators during the COVID-19 pandemic, Hamilton Medical established a new ventilator production site in Reno, Nevada, with the support of a local team from General Motors.

In four months, the facility moved from bare floor to full production, delivering the first of thousands of Hamilton-T1 ventilators purchased under contract by the U.S. Department of Health and Human Services (DHHS) in September 2020.

Get the full story at our sister site, Medical Design & Outsourcing.

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Ultrasonically welded flow sensor critical to success of Hamilton Medical ventilator design

The body of the Hamilton Medical proximal flow sensor consists of two molded halves composed of medical-grade plastic. Between the two halves, a ring-shaped insert holds a delicate membrane with a variable orifice that detects changes in air direction and flow within the patient airway, transmitting inhalation/exhalation inputs to the ventilator digital control through two small tubes linked to the ports at center right. These inputs are used to minutely regulate air pressure and flow in real time. [Photo courtesy of Hamilton Medical]

The disposable sensor monitors ventilation of critically ill patients with high precision.

Didier Perret, Emerson

Hamilton Medical (Bonaduz, Switzerland) produces intelligent ventilation solutions for intensive-care units and critical-care transports. To meet the exploding demand for ventilators during the COVID-19 pandemic, Hamilton Medical established a new ventilator produ…

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Equipment reliability is key to operational integrity in life sciences manufacturing

It’s difficult for a company to achieve excellence when batches are lost and maintenance crews must fight fires due to equipment failure. Still, solutions are available now to address these and other issues in the pharmaceutical industry.

Most life sciences plants and facilities face many issues impacting reliability, throughput, and uptime. For example, a bioreactor’s agitator slows down during a batch process without the operator realizing it, and the result is a quarantined batch and production schedule delay while it’s addressed.

In another common scenario, a unit’s control system says the pH of a given batch has moved out of its tolerance range, but plant personnel cannot quickly determine if it is due to a process upset or a malfunctioning sensor. Grab samples must be analyzed in the lab to verify, delaying production.

Or a pump used to empty a bioreactor at a critical time is malfunctioning. It may be a problem with the variable frequency drive, m…

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Plastics and medical devices: Changes for safety and cost

The move toward polypropylene and polyethylene in medical devices requires new manufacturing and assembly solutions such as ultrasonic and laser welding.

Didier Perret, Emerson

Emerson’s Branson GSX Ultrasonic Welding Platform [Photo courtesy of Emerson]

Plastics are ubiquitous in medical applications thanks to their light weight, durability and flexibility, among other attributes. However, concern has been increasing in recent years about the possible negative effects of some ingredients and components in certain plastics. This is leading medical-device companies to research and use other resins or combinations of plastics without the same risks. However, they do not have the same processing characteristic, and the changes often require companies to implement new production processes, especially around assembly and joining technologies.

For instance, polyvinyl chloride (PVC) is used in 40% of all …

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Emerson introduces new miniature rocker isolation valve for clinical lab instruments

Emerson ASCO Series 062 rocker isolation valves [Photo courtesy of Emerson]

Emerson (NYSE:EMR) has launched the ASCO Series 062 rocker isolation valve, designed for hematology and immunoassay analyzers, sample preparation and pre-analytical, as well as DNA sequencing instruments.

The St. Louis, Missouri-based company said the two-way and three-way valves are compact at 16mm, allowing for easy integration into complex fluid-handling manifolds while reducing their footprint, weight and power needs.

“The new ASCO Series 062 valves offer reliable and precise fluid control in a wide variety of analytical instrumentation and medical device applications,” Sven Richter, VP of analytical and medical at Emerson’s Automation Solutions business, said in a news release. “We understand that our original equipment manufacturer customers are under pressure to get products to market quickly, while improving production an…

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These technologies are speeding COVID-19 vaccines to market

Scientist working with a bioreactor for cell culture. Pharma manufacturing requires digitalization for best results, according to experts at Emerson. [Image courtesy of Emerson]

A combination of digital tools, improved production equipment, and advanced instrumentation helped COVID-19 vaccines to roll out in record time.

Ben Arriola and Zach Blum, Emerson

There is little doubt that researchers will study the COVID-19 pandemic and its effects from countless angles in the decades to come. Few events in modern times have had such global consequences, and the changes are far from over.

The most positive element of the story has been the speed with which many research organizations and pharmaceutical companies developed vaccines to prevent COVID-19. Usually, vaccines take years to develop and test. One of the latest examples of development from scratch was the mumps vaccine in the 1960s. It took four…

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Why wet storage is key for biopharmaceutical single-use pH sensor performance

For biopharmaceutical single-use applications, pH sensors designed for wet storage deliver needed long shelf life and one-point calibration.

Brandon Haschke, Emerson

Biopharmaceutical SUT manufacturing methods, which include disposable bioreactor bags, create challenges for performing analytical measurements such as pH. [Image courtesy of Emerson]

Biopharmaceutical processing applications, and especially single-use technology (SUT) manufacturing methods, present unique challenges for performing pH measurements. Quite often these processes are automated, and certainly they all must be monitored, so there is always a need to sense the process media pH.

SUT methods provide scalability and savings for manufacturers, in large part due to the use of durable and sterile disposable bioreactor bags. Instrumentation associated with SUT production must likewise be disposable, unless traditional sensors can…

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