Cortex initiates trial of mapping tech for AFib ablation

Cortex announced today that it began its RESOLVE-AF trial evaluating its Ablamap system with the newly release Ablacath mapping technology.

Launched by Ajax Health in December 2023, the company already offers the FDA-cleared Ablamap with electrographic flow (EGF). It seeks to pair the system with the newly released Ablacath mapping catheter to identify extra-pulmonary vein EGF sources.

Ablamap includes a workstation with software and monitor, amplifier and proprietary basket mapping catheter and cables.

EGF mapping allows physicians to detect EGF sources, leading to individualized ablation strategies and potentially improved outcomes. The trial aims to demonstrate that EGF mapping can identify EGF sources outside the pulmonary veins in all types of patients. That includes those with paroxysmal, persistent and long-standing persistent AFib, undergoing de novo or redo procedures.

RESOLVE-AF may enroll up to 400 subjects across more than 20 centers i…

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Ajax Health launches new pulsed-field ablation company called Cortex

Ajax Health announced today that it formed and provided funding for Cortex, a new developer of ablation technology for treating AFib.

Cortex launches with $90 million in funding commitments, led by KKR and Hellman & Friedman. AI Life Sciences and other investors also participated in this initial funding. KKR and H&F invested through the Cordis Accelerator, Cordis-X.

The new company brings together expert teams with complementary innovations in electrophysiology, according to a news release. It aims to accelerate the development and clinical validation of next-generation ablation solutions and AFib mapping technology.

The technology coming out of Cortex will be diagnostic and pulsed-field ablation (PFA) catheters. Ablacon’s Electrographic Flow mapping technology will provide comprehensive mapping and navigation capabilities. This mapping helps detect AFib sources, supporting personalized ablation therapy to potentially improve outcomes.

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