Two-armed surgical robot prototype targets pediatric brain tumors

The endoscopic brain robot’s arms are each 2.8 mm in diameter and 35 mm long when fully extended. Together, they offer a 43 mm diameter workspace. [Image courtesy of Boston Children’s Hospital]

Researchers say they’ve developed a surgical robot for removing brain tumors in children, and that it could also offer a less invasive, safer option for adult neurosurgery and other procedures.

The trick is using hollow, nitinol robot arms to allow neurosurgeons to swap tools during a tumor resection procedure, said Pierre DuPont. He’s the chief of pediatric cardiac bioengineering at Boston Children’s Hospital, and the corresponding author of a new research paper detailing the potential advantages of a two-armed neuroendoscopic robot.

In an interview with Medical Design & Outsourcing, DuPont traced the project back to conversations with Dr. Jim Drake, chief of neurosurgery at Sick…

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This T-cell vaccine could be the future of COVID-19 protection

[Image courtesy of Production Perig/Adobe Stock]

The current mRNA vaccines from Moderna (Nasdaq:MRNA) and Pfizer (NYSE:PFE)/BioNTech (Nasdaq:BNTX) stimulate the production of neutralizing antibodies that bind to the spike protein of SARS-CoV-2.

But there is a novel mRNA vaccine that activates T cells to attack cells infected with the virus. Developed by researchers at MIT and other institutions, the new vaccine could sidestep the need for updated boosters based on currently circulating variants.

In a preclinical study published in Frontiers in Immunology, the T-cell vaccine successfully attacked cells infected with the virus rather than activating the part of the immune system that releases neutralizing antibodies. In addition, the researchers tested the vaccine in humanized mice and successfully generated both CD8+ (cytotoxic) and CD4+ (helper) T-cell responses.

This new MIT-T-COVID vaccine could …

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