The 25 best-funded private healthcare and biotechnology companies of all time: From Altos to Theranos and beyond

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In early 2022, secretive Altos Labs stunned with a record $3 billion launch to pursue anti-aging “cellular rejuvenation” amid rumors of Jeff Bezos’ backing.

But a roundup of the 25 private healthcare and biotech companies that raised the most money in recent decades reveals a landscape of grand ambitions to disrupt healthcare. There are also some cautionary tales.

Included in the mix is scandal-plagued and now-liquidated Theranos, which raised a total of $1.4 billion in the early 2000s from prominent investors by fraudulently claiming to have game-changing blood testing technology.

Another company facing scrutiny is Devoted Health, a Medicare Advantage insurer that raised $1.9 billion aiming to reinvent senior care through technology and patient-centered approaches. STAT, however, noted that the company has yet to turn a profit after five years. And then there is Grail, wh…

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Moderna leans on RSV vaccine, AI and a diversified pipeline to regain competitive edge

Moderna surged to prominence thanks to its rapid development of a competitive COVID-19 vaccine. Since the early days of the pandemic, however, the company has struggled to maintain its momentum. Year-to-date, its stock is down close to 40%, trading around $110 per share.

Adapting to COVID-19 variants

The company hopes that its development of vaccines for the XBB.1.5 COVID-19 variant will help bolster financial performance. “We are now awaiting approval to start for our updated COVID-19 vaccine applications to regulators globally,” Moderna CEO Stéphane Bancel said.

Developing a robust pipeline

Moderna CEO Stéphane Bancel has stressed in the past that Moderna is more than a COVID-19 company. “Our commercial team is also preparing for the 2024 launch of our next respiratory commercial product,” Bancel said. This product in question, a vaccine for respiratory syncytial virus (RSV) could potentially compete against products from GSK and Pfizer, among others.

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