Modern ambient water for injection (AWFI) generation system [Image courtesy of CRB]
The pharma industry is in the process of moving toward ambient water for injection (WFI).Despite changes to regulations almost five years ago that allowed for alternative methods of generating WFI, the industry has been slow to fully embrace the shift away from traditional distillation despite the significant advantages of membrane-based WFI generation.
For companies with legacy distillation systems, the investment in new equipment for ambient WFI can be significant. Given its history, many pharmaceutical companies are familiar with the traditional distillation method.
In this article, industry experts from CRB, Chris Carlson and Jarrod Wrampe, describe the considerations to keep in mind when choosing between membrane-based WFI and traditional distillation for pharma applications.
Pro for membrane-based WFI …