[Image courtesy of catalin/Adobe Stock]
In recent years, the cell and gene therapy market has grown at a rapid clip. The momentum is likely to continue. According to Vision Research Reports, the global cell and gene therapy market size could hit around $42.56 billion by 2030, growing at a CAGR of 39% from 2022 to 2030.
The burgeoning demand in the industry, along with an increasing number of FDA-approved therapies, is also fueling the growth of cell and gene therapy vendors offering tools and services for product development and manufacturing.
The following table includes notable vendors and suppliers active in the call and gene therapy marketplace. This curated selection of companies includes a brief overview of their focus areas.
We have a separate feature focused on companies with prominent cell and gene therapy development efforts.
| Company Name | Description | Notable partnerships | Founded | Headquarters |
|---|---|---|---|---|
| 10X | Develops single-cell genomics and transcriptomics technology | Joined forces with Illumina for single-cell analysis | 2012 | Pleasanton, California |
| AGC Biologics | Offers cell line development, process development, and GMP manufacturing services for cell and gene therapies | Teamed up with Novavax for COVID-19 vaccine production | 2016 | Bothell, Washington |
| Akoya Biosciences | Develops multiplexed imaging technology for research and drug discovery | Cooperates with PerkinElmer for multiplex biomarker analysis | 2015 | Marlborough, Massachusetts |
| Aldevron | Provides plasmid DNA, RNA, and protein production services for gene therapy products | Worked with Sarepta Therapeutics for gene therapy production | 1998 | Fargo, North Dakota |
| Avectas | Develops non-viral cell engineering technology for the development of cell therapies | Collaborated with CCRM and the Canadian government for cell engineering technologies | 2011 | Kildare, Ireland |
| bluebird bio | Develops and manufactures gene therapies for the treatment of rare genetic diseases | Worked with Bristol Myers Squibb for gene therapy development and commercialization | 1992 | Cambridge, Massachusetts |
| Brammer Bio (Thermo Fisher Scientific) | Offers process development, clinical manufacturing, and regulatory support for gene and cell therapies | Working with Takeda to support gene therapy development and manufacturing | 2016 | Cambridge, Massachusetts |
| Catalent | Has a comprehensive cell therapy portfolio with expertise across various cell types | Teamed up with Moderna for COVID-19 vaccine production | 2007 | Somerset, New Jersey |
| Cellares | Offers a flexible and scalable cell and gene therapy manufacturing platform known as the Cell Shuttle | Collaborating with Sartorius to develop automated cell therapy manufacturing systems | 2020 | Cambridge, Massachusetts |
| CEVEC Pharmaceuticals | Provides cell line development services for gene therapy products | Allied with Paragon Bioservices for gene therapy production | 2004 | Cologne, Germany |
| Charles River Laboratories | Provides discovery and development services for cell and gene therapies, and provides cell line development services for gene therapy products | Working with AstraZeneca to provide various research and testing services | 1947 | Wilmington, Massachusetts |
| Cobra Biologics | Offers process development, scale-up, and GMP manufacturing services for viral vectors used in gene therapy | Joined forces with Karolinska Institute for cell and gene therapy development | 1998 | Keele, Stoke-on-Trent, United Kingdom |
| Codexis | Offers enzyme engineering services for the production of gene therapy vectors | Cooperates with Tate & Lyle for sweetener development and commercialization | 2002 | Redwood City, California |
| Cognate BioServices | Offers process development, manufacturing, and analytical services for cell and gene therapies | Teamed up with Astellas Pharma for gene therapy development and production | 2002 | Memphis, Tennessee |
| CRISPR Therapeutics | Develops gene therapies using CRISPR-Cas9 gene editing technology | Assisted Vertex Pharmaceuticals with gene therapy development and commercialization | 2013 | Cambridge, Massachusetts |
| Curate Biosciences | Launched the first microfluidics-based cell processing platform, improving the efficiency of patient apheresis and T-cell isolation, leading to better therapies and less engineering/manipulation needed down the line. | Collaborated with MaxCyte for cell therapy development | 2019 | South San Francisco, California |
| Fujifilm Cellular Dynamics | Develops and manufactures human cells used in cell therapy development, and other applications | Worked with UC San Francisco to develop iPSC-derived cell therapies | 1992 | Madison, Wisconsin |
| GeneWerk | Provides analytical services for the characterization of gene therapy vectors | Allied with Pfizer for gene therapy development and production | 2017 | Heidelberg, Germany |
| GenScript | Offers gene synthesis, molecular biology, and bio-manufacturing services for gene and cell therapies | Multiple partnerships for biologic, cancer immunotherapy, and CAR-T cell therapy development | 2002 | Piscataway, New Jersey |
| Lonza | The company’s Cocoon Platform is a closed, automated, and modular system for the manufacturing of cell and gene therapies | Teamed up with Moderna for COVID-19 vaccine production | 1897 | Basel, Switzerland |
| MaxCyte | Offers electroporation technology for the development of cell therapies | Collaborating with Apeiron Biologics for cell therapy development | 1998 | Gaithersburg, Maryland |
| MeiraGTx | Develops gene therapies for the treatment of rare genetic diseases | Worked with Janssen Pharmaceuticals for gene therapy development and commercialization | 2015 | New York City |
| Miltenyi Biotec | Offers cell and gene therapy products, as well as clinical and research solutions, including cell processing systems, cell isolation, and GMP manufacturing services | Working with bluebird bio for gene therapy development and production | 1989 | Bergisch Gladbach, Germany |
| Minaris Regenerative Medicine | A leading global contract development and manufacturing organization (CDMO) dedicated to the production of cell and gene therapy products | Joined forces with AstraZeneca for cell and gene therapy development and production | 2017 | Ottobrunn, Germany |
| Mission Bio | Develops single-cell sequencing technology for research and drug discovery | Cooperates with LabCorp for precision medicine solution development | 2014 | South San Francisco, California |
| Mustang Bio | Develops and manufactures cell and gene therapies for the treatment of cancer and genetic diseases | Teamed up with City of Hope for gene therapy development and commercialization | 2015 | Waltham, Massachusetts |
| Nanostring | Develops and manufactures genetic analysis technology | Partnered with Biogen for biomarker assay development | 2003 | Seattle, Washington |
| Ori Biotech | Offers a platform for cell and gene therapy manufacturing process development and optimization | Collaborates with Sartorius for cell therapy manufacturing platform development | 2015 | London, UK |
| Oxford Biomedica | Offers lentiviral vector development, process development, and GMP manufacturing services for gene and cell therapies | Worked with Novartis for gene therapy development and production | 1995 | Oxford,UK |
| Pluristem Therapeutics | Develops allogeneic cell therapies for the treatment of inflammatory and ischemic diseases | Working with NASA to study microgravity’s effects on cell therapy | 2001 | Haifa, Israel |
| Precision BioSciences | Develops gene therapies using its ARCUS gene editing technology | Allied with Servier for gene therapy development and commercialization | 2006 | Durham, North Carolina |
| Regenxbio | Provides gene therapy vector platforms and manufacturing services | Partnership with Adverum Biotechnologies for the development and production of gene therapies | 2008 | Rockville, Maryland |
| Resolve | Offers a platform for the automated manufacturing of cell therapies | Teamed up with AstraZeneca for cell therapy development and commercialization | 2013 | South San Francisco, California |
| Samsung Biologics | Offers cell line development, process development, and GMP manufacturing services for cell and gene therapies | Assisted Biogen with biologic production | 2011 | Incheon, South Korea |
| Sangamo Therapeutics | Develops gene therapies using zinc finger nuclease gene editing technology | Working with Pfizer for gene therapy development and commercialization | 1995 | Brisbane, California |
| Sarepta Therapeutics | Develops gene therapies for the treatment of genetic diseases | Collaborates with Roche for gene therapy development and commercialization | 1980 | Cambridge, Massachusetts |
| Spark Therapeutics (Roche) | Develops and manufactures gene therapies | Allied with Pfizer for gene therapy development and commercialization | 2013 | Philadelphia, Pennsylvania |
| Synthego | Offers gene editing tools, including CRISPR reagents and synthetic RNA for research and therapeutic applications | Worked with Twist Bioscience for the development and production of synthetic RNA | 2012 | Redwood City, California |
| Terumo BCT | Presented their first data since launching Quantum Flex, showing the capability to rapidly expand extracted T cells to make a dose, and its scalability for early research up through clinical batches. | Teamed up with Cognate BioServices for cell and gene therapy development | 1964 | Lakewood, Colorado |
| Thermo Fisher Scientific | Provides GMP plasmids, viral vectors, and cell and gene therapy manufacturing services through its Gibco, Aldevron, and Brammer Bio brands | Partnership with Hengrui Therapeutics for the development and commercialization of cancer immunotherapies | 1902 | Waltham, Massachusetts |