Cleveland

Downtown Cleveland skyline in 2022. Photo by Paul J. Heney.

With top-notch universities, federal research institutes, leading companies from nine major industry sectors, and 14 top-ranked hospital systems, Ohio is a “quiet giant” of innovation in industrial sectors and life science. Ohio has the fifth-highest number of Fortune 500 and Fortune 1000 companies — and is home to more than 120 NYSE/Nasdaq companies with a combined market capitalization exceeding $1 trillion.

Ohio government executives attribute the state’s growth to government actions that help businesses succeed and the research and development (R&D) investments that lay the foundation for innovation in the Midwest.

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